Role of methionine sulfoxide reductase in thermal-induced spreading depression coma in Drosophila melanogaster
Drosophila melanogaster encounter periods of increased temperature or decreased oxygen in its native environment. One consequence of these environmental stresses is increased production of reactive oxygen species that damage major molecules within cells. Another consequence is that flies fall into a...
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ndltd-fau.edu-oai-fau.digital.flvc.org-fau_39622019-07-04T03:51:03Z Role of methionine sulfoxide reductase in thermal-induced spreading depression coma in Drosophila melanogaster Schey, Karin. Text Electronic Thesis or Dissertation Florida Atlantic University English ix, 97 p. : ill. (some col.) electronic Drosophila melanogaster encounter periods of increased temperature or decreased oxygen in its native environment. One consequence of these environmental stresses is increased production of reactive oxygen species that damage major molecules within cells. Another consequence is that flies fall into a protective coma where biological functions are minimized to conserve energy expenditures. This biological phenomenon is called spreading depression. The overarching aim of this project is to determine if methionine sulfoxide reductases affect entrance or exit from the protective coma induced by acute thermal stress. The data revealed that complete deficiency of Msr in young flies causes a faster induction of the coma. In both young and old flies, Msr does not affect average recovery time but does affect the pattern of recovery from coma. Entrance into the coma is age dependent with young flies maintaining activity longer than before entering into the coma as compared to old flies. by Karin Schey. Thesis (M.S.)--Florida Atlantic University, 2012. Includes bibliography. Mode of access: World Wide Web. System requirements: Adobe Reader. Cellular signal transduction Proteins--Chemical modification Spreading cortical depression Oxidation-reduction reaction Aging--Molecular aspects Mutation (Biology) http://purl.flvc.org/FAU/3355873 820953151 3355873 FADT3355873 fau:3962 Charles E. Schmidt College of Science Department of Biological Sciences http://rightsstatements.org/vocab/InC/1.0/ https://fau.digital.flvc.org/islandora/object/fau%3A3962/datastream/TN/view/Role%20of%20methionine%20sulfoxide%20reductase%20in%20thermal-induced%20spreading%20depression%20coma%20in%20Drosophila%20melanogaster.jpg |
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English |
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Others
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Cellular signal transduction Proteins--Chemical modification Spreading cortical depression Oxidation-reduction reaction Aging--Molecular aspects Mutation (Biology) |
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Cellular signal transduction Proteins--Chemical modification Spreading cortical depression Oxidation-reduction reaction Aging--Molecular aspects Mutation (Biology) Role of methionine sulfoxide reductase in thermal-induced spreading depression coma in Drosophila melanogaster |
description |
Drosophila melanogaster encounter periods of increased temperature or decreased oxygen in its native environment. One consequence of these environmental stresses is increased production of reactive oxygen species that damage major molecules within cells. Another consequence is that flies fall into a protective coma where biological functions are minimized to conserve energy expenditures. This biological phenomenon is called spreading depression. The overarching aim of this project is to determine if methionine sulfoxide reductases affect entrance or exit from the protective coma induced by acute thermal stress. The data revealed that complete deficiency of Msr in young flies causes a faster induction of the coma. In both young and old flies, Msr does not affect average recovery time but does affect the pattern of recovery from coma. Entrance into the coma is age dependent with young flies maintaining activity longer than before entering into the coma as compared to old flies. === by Karin Schey. === Thesis (M.S.)--Florida Atlantic University, 2012. === Includes bibliography. === Mode of access: World Wide Web. === System requirements: Adobe Reader. |
author2 |
Schey, Karin. |
author_facet |
Schey, Karin. |
title |
Role of methionine sulfoxide reductase in thermal-induced spreading depression coma in Drosophila melanogaster |
title_short |
Role of methionine sulfoxide reductase in thermal-induced spreading depression coma in Drosophila melanogaster |
title_full |
Role of methionine sulfoxide reductase in thermal-induced spreading depression coma in Drosophila melanogaster |
title_fullStr |
Role of methionine sulfoxide reductase in thermal-induced spreading depression coma in Drosophila melanogaster |
title_full_unstemmed |
Role of methionine sulfoxide reductase in thermal-induced spreading depression coma in Drosophila melanogaster |
title_sort |
role of methionine sulfoxide reductase in thermal-induced spreading depression coma in drosophila melanogaster |
publisher |
Florida Atlantic University |
url |
http://purl.flvc.org/FAU/3355873 |
_version_ |
1719218931400441856 |