The importance of N-linked glycosylation on the N-domain of angiotensin-I converting enzyme
Angiotensin-I converting enzyme (ACE) is an important drug target in the treatment of heart disease due to its role in the regulation of blood pressure. ACE contains two domains, the N- and C-domains, both of which are catalytically active and heavily glycosylated. Glycosylation is one of the most i...
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Doctoral Thesis |
| Language: | English |
| Published: |
University of Cape Town
2014
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/11427/10051 |