Semi-synthesis and evaluation of fusidic acid derivatives as potential antituberculosis agents
The causative agent of tuberculosis (TB), Mycobacterium tuberculosis (Mtb), still remains one of the most serious infectious diseases with 10 million new reported cases in 2015. Although TB is curable, the ability to acquire resistance to various antibiotics by the Mtb organism is well known. The em...
Main Author: | Shanika, Petrus Siningu |
---|---|
Other Authors: | Chibale, Kelly |
Format: | Dissertation |
Language: | English |
Published: |
University of Cape Town
2018
|
Subjects: | |
Online Access: | http://hdl.handle.net/11427/27536 |
Similar Items
-
In vitro metabolism of tetrazole aminoquinolines and derivatives of metergoline and fusidic acid
by: Njoroge, Mathew
Published: (2015) -
Repositioning fusidic acid for tuberculosis: semi-synthesis of analogues and impact of mycobacterial biotransformation on antibiotic activity
by: Wasuna, Antonina
Published: (2018) -
Riminophenazine Derivatives as Potential Antituberculosis Agents: Synthesis, Biological, and Electrochemical Evaluations
by: Mpelegeng Victoria Bvumbi, et al.
Published: (2021-07-01) -
Developing methods to prioritize in vitro drug combinations against Mycobacterium tuberculosis: fusidic acid as potential combination partner with known antitubercular agents
by: Omollo, Charles
Published: (2017) -
The biological evaluation of fusidic acid and its hydrogenation derivative as antimicrobial and anti-inflammatory agents
by: Wu PP, et al.
Published: (2018-10-01)