Hereditary non-polyposis colorectal carcinoma (HNPCC) : morphological and immunohistochemical studies

• Main Author: Holm, Hannes
• Other Authors: Hall, Pauline de la Motte
• Format: Dissertation
• Language: English
• Published: University of Cape Town 2014
• Subjects: Anatomical Pathology
• Online Access: http://hdl.handle.net/11427/3079

Includes bibliographical references. === Families with hereditary non-polyposis colorectal carcinoma (HNPCC) are not uncommon along the West-Coast of South Africa. These patients present with early onset carcinomas mostly colorectal, predominantly in the right colon. They may develop tumours of other organs, including uterus, breast, stomach and skin. To evaluate and compare the microscopic characteristics of three groups of colorectal carcinomas (HNPCC, early onset colorectal carcinomas and sporadic colorectal carcinomas). 2. To determine the features most characteristic of the group.