Investigating the role of IL-4/IL-13 and their receptors in ulcerative colitis
Ulcerative colitis (UC) is a heterogeneous inflammatory bowel disease (IBD) associated with chronic inflammation of the gastrointestinal tract. Characterized by genetic and immunological abnormalities, UC has overly aggressive T-cell responses to commensal bacteria eventually leading to disease path...
Main Author: | Hoving, J Claire |
---|---|
Other Authors: | Brombacher, Frank |
Format: | Doctoral Thesis |
Language: | English |
Published: |
University of Cape Town
2014
|
Subjects: | |
Online Access: | http://hdl.handle.net/11427/3164 |
Similar Items
-
Immune and allergic responses to Anisakis pegreffii, with focus on the roles of IL-4, IL-13 and the IL-4 receptor alpha
by: Nieuwenhuizen, Natalie
Published: (2014) -
Targeting IL-13 as a Host-Directed Therapy Against Ulcerative Colitis
by: J. Claire Hoving
Published: (2018-11-01) -
Investigating the role of IL-4/IL-13 signalling through the IL-4 receptor alpha (IL-4Rα) on keratinocytes in murine models of Leishmania major and Schistosoma mansoni
by: Govender, Melissa
Published: (2017) -
The role of IL-4 and IL-13 responsiveness during Schistosoma mansoni induced inflammation
by: Marillier, Reece Gerrad
Published: (2014) -
The role of IL-4 and IL-13 in pulmonary tuberculosis using gene-deficient mice and protective efficacy of the purine-deficient auxotroph of Mycobacterium tuberculosis
by: Brown, Najmeeyah
Published: (2014)