Characterisation of the role of brain factor 1 in the olfactory neuroepithelium during neuronal development
Bibliography: leaves 147-152. === Brain Factor 1 (BF-1), a winged helix transcription factor, displays a restricted pattern of expression within the developing forebrain, playing a critical function in the regulation of neuronal progenitor cell proliferation and differentiation within the developing...
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| Format: | Dissertation |
| Language: | English |
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University of Cape Town
2014
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| Online Access: | http://hdl.handle.net/11427/5967 |
| Summary: | Bibliography: leaves 147-152. === Brain Factor 1 (BF-1), a winged helix transcription factor, displays a restricted pattern of expression within the developing forebrain, playing a critical function in the regulation of neuronal progenitor cell proliferation and differentiation within the developing forebrain. The molecular mechanisms by which BF-1 carries out its function remain to be elucidated. Hence, this study aimed to investigate and characterise the molecular mechanisms by which BF-1 function is regulated during neuronal development. |
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