Growth and immunity of weaner piglets supplemented with dietary tryptophan, threonine and glutamine

• Main Author: Greaves, Stenelle
• Other Authors: Jansen van Rensburg, Christine
• Language: en
• Published: University of Pretoria 2016
• Subjects: UCTD
• Online Access: http://hdl.handle.net/2263/53496; Greaves, S 2016, Growth and immunity of weaner piglets supplemented with dietary tryptophan, threonine and glutamine, MSc Dissertation, University of Pretoria, Pretoria, viewed yymmdd <http://hdl.handle.net/2263/53496>

Post-weaning mortality has a major economic implication for pig producers. Post-weaning stress is influenced by a number of factors, including the piglets inherent ability and physiological mechanisms to adapt to the new environment. Various amino acids, including threonine, tryptophan and glutamine, have been shown to have a positive effect on the immune system. Higher inclusion levels than current commercial standards of threonine, tryptophan or glutamine and different combinations of these, were mixed into a basal weaner diet to create eight dietary treatments. 48 crossbred piglets (Landrace x Large White) were included in a 28 day growth trail shortly after wean, with six piglets per treatment. Body weight gain, feed intake and feed conversion efficiency (FCE) were measured weekly. At the onset of the trial, piglets were injected with a 10% ovine erythrocyte suspension as an immune challenge. Blood samples from each piglet were collected at 7 day intervals to obtain antibody titre values against ovine erythrocytes. In general, amino acid concentrations used in this study did not result in significant differences (P>0.05) between treatments except for a significant decrease in both body weight gain and FCE when higher concentrations of threonine were fed. However, higher antibody values against sheep erythrocytes were noted in piglets when they received additional threonine in their feed (P>0.05). The results of this trial were not conclusive, but indicated a negative impact of high threonine levels on the production performance of the piglets, while simultaneously improving the production of antibodies against foreign protein molecules, which could support the health of piglets during the post-weaning period. === Dissertation (MSc)--University of Pretoria, 2015. === Animal and Wildlife Sciences === MSc === Unrestricted