Synthesis and evaluation of novel coumarin-donepezil derivatives as dual acting monoamine oxidase B and cholinesterase in Alzheimer's disease
Magister Pharmaceuticae - MPharm === Alzheimer's disease is a progressive neurodegenerative disease characterised by low acetylcholine (ACh) levels in the hippocampus and cortex of the brain, causing symptoms like progressive memory loss, decline in language skills and other cognitive impairmen...
Main Author: | Foka, Germaine Boulenoue |
---|---|
Other Authors: | Joubert, J. |
Language: | en |
Published: |
University of the Western Cape
2017
|
Subjects: | |
Online Access: | http://hdl.handle.net/11394/5549 |
Similar Items
-
Molecular docking studies of coumarin hybrids as potential acetylcholinesterase, butyrylcholinesterase, monoamine oxidase A/B and β-amyloid inhibitors for Alzheimer’s disease
by: Samina Khan Yusufzai, et al.
Published: (2018-12-01) -
Synthesis and evaluation of 7-substituted 3-propargylamine coumarin derivatives as multifunctional monoamine oxidase and cholinesterase inhibitors for Alzheimer’s Disease treatme
by: Mzezewa, Sheunopa C.
Published: (2020) -
Role of Monoamine Oxidase Activity in Alzheimer’s Disease: An Insight into the Therapeutic Potential of Inhibitors
by: Tapan Behl, et al.
Published: (2021-06-01) -
4-Phenethyl-1-Propargylpiperidine-Derived Dual Inhibitors of Butyrylcholinesterase and Monoamine Oxidase B
by: Tjaša Mazej, et al.
Published: (2021-07-01) -
Hospitalized Patients' Perceived Knowledge and Risk of Monoamine Oxidase Inhibitor Medications Before and After a Pharmacist's Classroom-Based Education
by: Richard G. Wenzel, et al.
Published: (2010-06-01)