Investigation of the role of the ubiquitin-like DWNN domain in targeting Retinoblastoma Binding Protein 6 to nuclear speckles

Retinoblastoma Binding Protein 6 (RBBP6) is a 200 KDa protein shown to play a role in 3'- polyadenylation of mRNA transcripts, as well as to function as an E3 ligase catalysing ubiquitination of cancer-associated proteins. RBBP6 has been previously reported to localise to nuclear speckles, w...

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Bibliographic Details
Main Author: Mlaza, Mihlali
Other Authors: Pugh, David J.R.
Language:en
Published: University of the Western Cape 2018
Subjects:
Online Access:http://hdl.handle.net/11394/6200

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