Design and synthesis of new scaffolds as antiproliferative agents and potential hsp90 inhibitors

Doctor Pharmaceuticae - DPharm === Natural products have been an important source of drugs and novel lead compounds in drug discovery. Their unique scaffolds have led to the synthesis of derivatives that continue to give rise to medicinally relevant agents. Thus, natural product-inspired drugs rep...

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Main Author:	Adegoke, Yusuf Adeyemi
Other Authors:	Beukes, Denzil R.
Language:	en
Published:	University of Western Cape 2020
Subjects:	Asparagine Dichloromethane Correlation spectroscopy Deuterated chloroform Hsp90 inhibitors
Online Access:	http://hdl.handle.net/11394/7722

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spelling	ndltd-netd.ac.za-oai-union.ndltd.org-uwc-oai-etd.uwc.ac.za-11394-77222021-01-03T05:10:53Z Design and synthesis of new scaffolds as antiproliferative agents and potential hsp90 inhibitors Adegoke, Yusuf Adeyemi Beukes, Denzil R. Asparagine Dichloromethane Correlation spectroscopy Deuterated chloroform Hsp90 inhibitors Doctor Pharmaceuticae - DPharm Natural products have been an important source of drugs and novel lead compounds in drug discovery. Their unique scaffolds have led to the synthesis of derivatives that continue to give rise to medicinally relevant agents. Thus, natural product-inspired drugs represent a significant proportion of drugs in the market and with several more in development. Cancer is among the leading public health problems and a prominent cause of death globally. Chemotherapy has been important in the management of this disease even though side effects that arise due to lack of selectivity is still an issue. 2020-12-09T13:00:09Z 2021-01-01T22:10:05Z 2020 http://hdl.handle.net/11394/7722 en University of Western Cape University of Western Cape
collection	NDLTD
language	en
sources	NDLTD
topic	Asparagine Dichloromethane Correlation spectroscopy Deuterated chloroform Hsp90 inhibitors
spellingShingle	Asparagine Dichloromethane Correlation spectroscopy Deuterated chloroform Hsp90 inhibitors Adegoke, Yusuf Adeyemi Design and synthesis of new scaffolds as antiproliferative agents and potential hsp90 inhibitors
description	Doctor Pharmaceuticae - DPharm === Natural products have been an important source of drugs and novel lead compounds in drug discovery. Their unique scaffolds have led to the synthesis of derivatives that continue to give rise to medicinally relevant agents. Thus, natural product-inspired drugs represent a significant proportion of drugs in the market and with several more in development. Cancer is among the leading public health problems and a prominent cause of death globally. Chemotherapy has been important in the management of this disease even though side effects that arise due to lack of selectivity is still an issue.
author2	Beukes, Denzil R.
author_facet	Beukes, Denzil R. Adegoke, Yusuf Adeyemi
author	Adegoke, Yusuf Adeyemi
author_sort	Adegoke, Yusuf Adeyemi
title	Design and synthesis of new scaffolds as antiproliferative agents and potential hsp90 inhibitors
title_short	Design and synthesis of new scaffolds as antiproliferative agents and potential hsp90 inhibitors
title_full	Design and synthesis of new scaffolds as antiproliferative agents and potential hsp90 inhibitors
title_fullStr	Design and synthesis of new scaffolds as antiproliferative agents and potential hsp90 inhibitors
title_full_unstemmed	Design and synthesis of new scaffolds as antiproliferative agents and potential hsp90 inhibitors
title_sort	design and synthesis of new scaffolds as antiproliferative agents and potential hsp90 inhibitors
publisher	University of Western Cape
publishDate	2020
url	http://hdl.handle.net/11394/7722
work_keys_str_mv	AT adegokeyusufadeyemi designandsynthesisofnewscaffoldsasantiproliferativeagentsandpotentialhsp90inhibitors
_version_	1719371946890625024

Design and synthesis of new scaffolds as antiproliferative agents and potential hsp90 inhibitors

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