Geneticky podmíněná variabilita metabolizmu léčiv

Drug metabolism is one of the key processes allowing to eliminate the administered dose. High interindividual variability of the activity of drug metabolizing enzymes is caused by many genetic and epigenetic factors. This variation can result in substantial differences in clinical response to the dr...

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Bibliographic Details
Main Author: Slanař, Ondřej
Other Authors: Perlík, František
Format: Doctoral Thesis
Language:Czech
Published: 2007
Online Access:http://www.nusl.cz/ntk/nusl-271400