Prevence vzniku diabetes mellitus 1. typu v dětském věku
Type 1 diabetes mellitus is among autoimmune disease that primarily affects children and young people. when This disease leads to the destruction of B-cells Pancreatic islets of Langerhans which are responsible for insulin secretion. Its deficiency leads to disturbances metabolism of carbohydrates a...
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2008
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Online Access: | http://www.nusl.cz/ntk/nusl-273132 |
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ndltd-nusl.cz-oai-invenio.nusl.cz-2731322018-10-03T04:29:17Z Prevence vzniku diabetes mellitus 1. typu v dětském věku Prevention of Diabetes Mellitus I. type in childhood Doudová, Šárka Černá, Marie Type 1 diabetes mellitus is among autoimmune disease that primarily affects children and young people. when This disease leads to the destruction of B-cells Pancreatic islets of Langerhans which are responsible for insulin secretion. Its deficiency leads to disturbances metabolism of carbohydrates and other nutrients . The destruction of B- cells occurs gradually and the first clinical symptoms appear only when destruction of a percentage of B- cells of the pancreas . after the outbreak difficulties the patient becomes dependent on exogenous life insulin administration . The incidence of type 1 diabetes mellitus is increasing worldwide and There are significant differences between geographic countries. This suggests that the pathogenesis of the disease have undoubtedly a great influence environmental factors. important role Genetic factors also play a immunological mechanisms. In my work I try to outline the possibilities of prevention as it related prediction type 1 diabetes mellitus . describe primarily genetic , and immunological markers , which can be used to predict genetic risk and to monitor the period before the manifestation of the disease. I mention also the possibilities of primary prevention, which is not currently yet only at the experimental field. Within the secondary Prevention describes... 2008 info:eu-repo/semantics/masterThesis http://www.nusl.cz/ntk/nusl-273132 cze info:eu-repo/semantics/restrictedAccess |
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NDLTD |
language |
Czech |
format |
Dissertation |
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NDLTD |
description |
Type 1 diabetes mellitus is among autoimmune disease that primarily affects children and young people. when This disease leads to the destruction of B-cells Pancreatic islets of Langerhans which are responsible for insulin secretion. Its deficiency leads to disturbances metabolism of carbohydrates and other nutrients . The destruction of B- cells occurs gradually and the first clinical symptoms appear only when destruction of a percentage of B- cells of the pancreas . after the outbreak difficulties the patient becomes dependent on exogenous life insulin administration . The incidence of type 1 diabetes mellitus is increasing worldwide and There are significant differences between geographic countries. This suggests that the pathogenesis of the disease have undoubtedly a great influence environmental factors. important role Genetic factors also play a immunological mechanisms. In my work I try to outline the possibilities of prevention as it related prediction type 1 diabetes mellitus . describe primarily genetic , and immunological markers , which can be used to predict genetic risk and to monitor the period before the manifestation of the disease. I mention also the possibilities of primary prevention, which is not currently yet only at the experimental field. Within the secondary Prevention describes... |
author2 |
Černá, Marie |
author_facet |
Černá, Marie Doudová, Šárka |
author |
Doudová, Šárka |
spellingShingle |
Doudová, Šárka Prevence vzniku diabetes mellitus 1. typu v dětském věku |
author_sort |
Doudová, Šárka |
title |
Prevence vzniku diabetes mellitus 1. typu v dětském věku |
title_short |
Prevence vzniku diabetes mellitus 1. typu v dětském věku |
title_full |
Prevence vzniku diabetes mellitus 1. typu v dětském věku |
title_fullStr |
Prevence vzniku diabetes mellitus 1. typu v dětském věku |
title_full_unstemmed |
Prevence vzniku diabetes mellitus 1. typu v dětském věku |
title_sort |
prevence vzniku diabetes mellitus 1. typu v dětském věku |
publishDate |
2008 |
url |
http://www.nusl.cz/ntk/nusl-273132 |
work_keys_str_mv |
AT doudovasarka prevencevznikudiabetesmellitus1typuvdetskemveku AT doudovasarka preventionofdiabetesmellitusitypeinchildhood |
_version_ |
1718758781581524992 |