| Summary: | 1 Abstract. ĽUPTÁK, P. Antimicrobial effect of photocalatic effective compounds of metals. Diploma work. Faculty of Pharmacy in Hradec Králové, Charles University, 2009. Field of study: Pharmacy, Background This diploma work is aimed at testing antimicrobial activity coatings on the basis of photocalytic effect of nano particles of metal dioxides. In the coats tested active nano particles of tantium dioxide alone or with zinc oxide were used. Methods In this work we have developed a methodics, which is in the experimental part. The methodics contains three ways, in which the coats have been mutually compared on the basis of activation of UV-VIS radiation: A method of in advance radiated coats with antimicrobial activity for three hours. A method of radiation of the coats with antimicrobial activity with applied suspension. A method of radiation of coats in advance with microbial activity for various time periods. The effectiveness have been tested on five microorganisms Escherichia coli, Staphylococus auereus, Pseudomonas aeruginosa, Bacilus subtilis and Candida albicans as the representative of eukaryotic organisms. Results At all methods G- microorganisms were more sensitive, which showed the sensitivity even without UV-VIS radiation. After longer time periods of contact G+ organisms were well...
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