Studium vlivu selenu na proliferaci buněčných linií izolovaných z kolorektálního karcinomu
Selenium is an essential trace element that is an integral part of many proteins, with catalytic and structural functions. The antioxidant properties of some selenoproteins, such as glutathione peroxidase, may be particularly important in having influence on carcinogenesis. Selenium exists in differ...
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Dissertation |
| Language: | Czech |
| Published: |
2008
|
| Online Access: | http://www.nusl.cz/ntk/nusl-292554 |
| id |
ndltd-nusl.cz-oai-invenio.nusl.cz-292554 |
|---|---|
| record_format |
oai_dc |
| spelling |
ndltd-nusl.cz-oai-invenio.nusl.cz-2925542017-09-02T04:15:51Z Studium vlivu selenu na proliferaci buněčných linií izolovaných z kolorektálního karcinomu The study of effect of selenium on proliferation of cell lines isolated from colorectal carcinoma Žmolilová, Hana Szotáková, Barbora Šimůnek, Tomáš Selenium is an essential trace element that is an integral part of many proteins, with catalytic and structural functions. The antioxidant properties of some selenoproteins, such as glutathione peroxidase, may be particularly important in having influence on carcinogenesis. Selenium exists in different chemical forms - inorganic (selenite, selenate) and organic forms (selenoaminoacids, selenoproteins). The bioavailability and cancer chemoprotective activity of selenium depend on the concentration and the chemical form in which it is present. I studied the effect of L-Selenomethionine and Se-methyl-L-selenocysteine on proliferation in three colorectal cell lines with different malignant potential (HT 29, SW 480, SW 620). Proliferation was measured by BrdU - ELISA with chemiluminiscent detection. 2008 info:eu-repo/semantics/masterThesis http://www.nusl.cz/ntk/nusl-292554 cze info:eu-repo/semantics/restrictedAccess |
| collection |
NDLTD |
| language |
Czech |
| format |
Dissertation |
| sources |
NDLTD |
| description |
Selenium is an essential trace element that is an integral part of many proteins, with catalytic and structural functions. The antioxidant properties of some selenoproteins, such as glutathione peroxidase, may be particularly important in having influence on carcinogenesis. Selenium exists in different chemical forms - inorganic (selenite, selenate) and organic forms (selenoaminoacids, selenoproteins). The bioavailability and cancer chemoprotective activity of selenium depend on the concentration and the chemical form in which it is present. I studied the effect of L-Selenomethionine and Se-methyl-L-selenocysteine on proliferation in three colorectal cell lines with different malignant potential (HT 29, SW 480, SW 620). Proliferation was measured by BrdU - ELISA with chemiluminiscent detection. |
| author2 |
Szotáková, Barbora |
| author_facet |
Szotáková, Barbora Žmolilová, Hana |
| author |
Žmolilová, Hana |
| spellingShingle |
Žmolilová, Hana Studium vlivu selenu na proliferaci buněčných linií izolovaných z kolorektálního karcinomu |
| author_sort |
Žmolilová, Hana |
| title |
Studium vlivu selenu na proliferaci buněčných linií izolovaných z kolorektálního karcinomu |
| title_short |
Studium vlivu selenu na proliferaci buněčných linií izolovaných z kolorektálního karcinomu |
| title_full |
Studium vlivu selenu na proliferaci buněčných linií izolovaných z kolorektálního karcinomu |
| title_fullStr |
Studium vlivu selenu na proliferaci buněčných linií izolovaných z kolorektálního karcinomu |
| title_full_unstemmed |
Studium vlivu selenu na proliferaci buněčných linií izolovaných z kolorektálního karcinomu |
| title_sort |
studium vlivu selenu na proliferaci buněčných linií izolovaných z kolorektálního karcinomu |
| publishDate |
2008 |
| url |
http://www.nusl.cz/ntk/nusl-292554 |
| work_keys_str_mv |
AT zmolilovahana studiumvlivuselenunaproliferacibunecnychliniiizolovanychzkolorektalnihokarcinomu AT zmolilovahana thestudyofeffectofseleniumonproliferationofcelllinesisolatedfromcolorectalcarcinoma |
| _version_ |
1718525165087752192 |