Statistické metody pro interpretaci forenzních DNA směsí

• Main Author: Kubátová, Helena
• Other Authors: Zvárová, Jana
• Format: Dissertation
• Language: Czech
• Published: 2010
• Online Access: http://www.nusl.cz/ntk/nusl-298936

In the present work we study interpretation of forensic DNA evidence from the point of view of probability theory and mathematical statistics. We provide a detailed mathematical formalization of the problem, which enables us to formulate mathematically accurate and consistent results. We deal with evaluation of a given evidence in terms of a likelihood ratio, which compares two hypotheses speci ed by genotypes of known contributors and the number of unknown contributors to the DNA mixture. We further analyze the case of a subdivided population, performing a thorough revision of the formulas for homozygous and heterozygous genotypes, their general version and a theorem for calculating the probability that an assumed number of random individuals explain a given genetic evidence.