| Summary: | Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Biological and Medical Sciences Candidate: Bc. Šárka Fenclová Supervisor: MUDr. Pavla Paterová Title of diploma thesis: Occurence of multidrug-resistant Pseudomonas aeruginosa in University Hospital Hradec Králové Multidrug-resistant strains of Pseudomonas aeruginosa are increasingly frequent threat especially among nosocomial pathogens. Therapy of infections caused by the microbe becomes a problem has occurred and even when there is no effective antibiotic. The content of this thesis is a summary of knowledge of the bacterium, its diagnosis, treatment and epidemiology of infections. The experimental part focuses on the overall incidence of multidrug-resistant Pseudomonas aeruginosa, and as multiresistant this bacterium was evaluated in resistance to at least 3 of the 6 anti-pseudomonas used antibiotics, for the years 2012 - 2014. It is also evaluated the number of new cases of multidrug-resistant Pseudomonas aeruginosa for the years 2012-2014 which is divided according to the type of material, according clinics, by subject, age and sex of the patient and the period of coverage. The final character was observed phenotypic antibiotic resistance for the years 2008 - 2014, together with the consumption of antibiotics in...
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