Protinádorová aktivita a toxicita konjugátů na bázi HPMA kopolymerů nesoucí cytostatikum

7 ABSTRACT In this study, we addressed the biological activity and pharmacological features of selected HPMA copolymer-based drug conjugates. We determined their cytostatic activity in vitro as well as toxicity in vivo and therapeutic effcicacy in mouse tumor models. Assessment of maximum tolerate...

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Bibliographic Details
Main Author: Tomalová, Barbora
Other Authors: Kovář, Marek
Format: Doctoral Thesis
Language:English
Published: 2018
Online Access:http://www.nusl.cz/ntk/nusl-380319