Pokus o charakterizaci proteinu vázajícího TNF - \recke{alpha} ve slinách klíštěte \kur{Ixodes ricinus}

Pokus o charakterizaci proteinu vázajícího TNF - \recke{alpha} ve slinách klíštěte \kur{Ixodes ricinus}

Tumor necrosis factor is one of the most important pro-inflammatory cytokines of the innate immune system. We tested several species of ticks for anti-tumour necrosis factor- activity in this study. The specific activity was proved for Ixodes ricinus saliva and several other species. We also tested...

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Main Author: REZKOVÁ, Markéta
Format: Dissertation
Language:Czech
Published: 2017
Online Access:http://www.nusl.cz/ntk/nusl-381486
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spelling ndltd-nusl.cz-oai-invenio.nusl.cz-3814862018-10-04T16:45:22Z Pokus o charakterizaci proteinu vázajícího TNF - \recke{alpha} ve slinách klíštěte \kur{Ixodes ricinus} REZKOVÁ, Markéta Tumor necrosis factor is one of the most important pro-inflammatory cytokines of the innate immune system. We tested several species of ticks for anti-tumour necrosis factor- activity in this study. The specific activity was proved for Ixodes ricinus saliva and several other species. We also tested dynamics of this specific activity in Ixodes ricinus saliva. The highest effect of saliva appears at the end of feeding period. Although we detected an inhibitory effect, none TNF-binding molecule has been identified so far. Our results excluded enzymatic aktivity cleaving TNF molecule. 2017 info:eu-repo/semantics/masterThesis http://www.nusl.cz/ntk/nusl-381486 cze info:eu-repo/semantics/restrictedAccess
collection NDLTD
language Czech
format Dissertation
sources NDLTD
description Tumor necrosis factor is one of the most important pro-inflammatory cytokines of the innate immune system. We tested several species of ticks for anti-tumour necrosis factor- activity in this study. The specific activity was proved for Ixodes ricinus saliva and several other species. We also tested dynamics of this specific activity in Ixodes ricinus saliva. The highest effect of saliva appears at the end of feeding period. Although we detected an inhibitory effect, none TNF-binding molecule has been identified so far. Our results excluded enzymatic aktivity cleaving TNF molecule.
author REZKOVÁ, Markéta
spellingShingle REZKOVÁ, Markéta
Pokus o charakterizaci proteinu vázajícího TNF - \recke{alpha} ve slinách klíštěte \kur{Ixodes ricinus}
author_facet REZKOVÁ, Markéta
author_sort REZKOVÁ, Markéta
title Pokus o charakterizaci proteinu vázajícího TNF - \recke{alpha} ve slinách klíštěte \kur{Ixodes ricinus}
title_short Pokus o charakterizaci proteinu vázajícího TNF - \recke{alpha} ve slinách klíštěte \kur{Ixodes ricinus}
title_full Pokus o charakterizaci proteinu vázajícího TNF - \recke{alpha} ve slinách klíštěte \kur{Ixodes ricinus}
title_fullStr Pokus o charakterizaci proteinu vázajícího TNF - \recke{alpha} ve slinách klíštěte \kur{Ixodes ricinus}
title_full_unstemmed Pokus o charakterizaci proteinu vázajícího TNF - \recke{alpha} ve slinách klíštěte \kur{Ixodes ricinus}
title_sort pokus o charakterizaci proteinu vázajícího tnf - \recke{alpha} ve slinách klíštěte \kur{ixodes ricinus}
publishDate 2017
url http://www.nusl.cz/ntk/nusl-381486
work_keys_str_mv AT rezkovamarketa pokusocharakterizaciproteinuvazajicihotnfreckealphaveslinachklistetekurixodesricinus
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