| Summary: | Physiotherapy has the potential to interfere with the neuroendocrine-immune system through natural stimuli, and thus regulate complex neuroimmune processes in the central nervous system. The ability to target the immune and endocrine systems through physical activity and physiotherapy could slow disease progression, streamline tertiary prevention of the development of clinical manifestations of the disease, disability, loss of self-sufficiency, and improve patients' quality of life. So far, only a few pilot projects have been implemented. One of them was our previous study, which allows modulating the immune and endocrine system using the methods Motor programme activating therapy - physiotherapeutic methods using neurophysiological knowledge (belongs to the category of neuroproprioceptive facilitation and inhibition). In this study, we increased the number of participants and included another physiotherapeutic method from the same category, Vojta's reflex locomotion. 44 patients with multiple sclerosis were randomly divided into two groups. Each underwent a different type of two-month outpatient neuroproprioceptive "facilitation and inhibition" physiotherapy (Motor programs activating therapy and Vojta's reflex locomotion). Over the next two months, participants continued autotherapy. We primarily...
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