Intercellular calcium-mediated cell signaling in keratinocytes cultured from patients with NF1 or psoriasis
Abstract Neurofibromatosis type 1 syndrome (NF1) is caused by mutations of the NF1 gene. The NF1 protein (neurofibromin) contains a domain which is related to the GTPase-activating protein (GAP) and accelerates the switch of active Ras-GTP to inactive Ras-GDP. The NF1 protein has been referred...
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Format: | Doctoral Thesis |
Language: | English |
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University of Oulu
2002
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Online Access: | http://urn.fi/urn:isbn:9514268040 http://nbn-resolving.de/urn:isbn:9514268040 |