Des cyclobutanones chirales vers la (-)-Salinosporamide A

Des cyclobutanones chirales vers la (-)-Salinosporamide A

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Le travail présenté dans ce manuscrit concerne le développement d'une nouvelle voie d'accès à une famille de butyrolactames naturels à fort potentiel thérapeutique basé sur une réaction de cycloaddition [2+2] suivie d'une expansion de cycle. Dans la partie principale, une méthodologie...

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Bibliographic Details
Main Author:	Grisel, Julien
Other Authors:	Grenoble
Language:	fr
Published:	2012
Subjects:	Cycloaddition Cétène symétrique Cétène dissymétrique Produits naturels Lactame Expansion de cycle Symmetric ketene Unsymmetric ketene Natural products Cycle expansion
Online Access:	http://www.theses.fr/2012GRENV058/document

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