Role of thymidine phosphorylase and Nrf2 transcription factor in non-small cell lung carcinoma growth and angiogenesis

Role of thymidine phosphorylase and Nrf2 transcription factor in non-small cell lung carcinoma growth and angiogenesis

Le facteur de transcription Nrf2 et les enzymes pro-angiogéniques: hème oxygénase (HO-1) et thymidine phosphorylase (TP) sont considérés comme des cibles potentielles pour les traitements combinatoires anticancéreux contre l’angiogenèse. L'objectif de la présente étude était d'examiner les...

Full description

Bibliographic Details
Main Author:	Tertil, Magdalena
Other Authors:	Orléans
Language:	en
Published:	2013
Subjects:	Thymidine phosphorylase Facteur de transcription Nrf2 Carcinome pulmonaire non à petites cellules Angiogenèse Transcription factor Nrf2 Non-small cell lung carcinoma growth Angiogenesis
Online Access:	http://www.theses.fr/2013ORLE2043

Similar Items

Thymidine Catabolism as a Metabolic Strategy for Cancer Survival
by: Sho Tabata, et al.
Published: (2017-05-01)

Thymidine phosphorylase and its possible correlation with the lung cancer phenotype features
by: E. M. Bakurova, et al.
Published: (2015-04-01)

Research development of the relationship between thymidine phosphorylase expression and colorectal carcinoma
by: Dian-Jun Ye, et al.
Published: (2013-03-01)

Lipid Peroxidation and Thymidine Phosphorylase expression in Prostate Carcinoma
by: Tandon R., et al.
Published: (2012-08-01)

Determining the specific activity of thymidine phosphorylase in leukocytes of patients with MNGIE and the plasma thymidine level by RP-HPLC
by: Rezaei Sh, et al.
Published: (2011-06-01)

Synthesis of Thymidine Phosphorylase Inhibitor Based on Quinoxaline Derivatives and Their Molecular Docking Study
by: Noor Barak Almandil, et al.
Published: (2019-03-01)

Hemodialysis in MNGIE transiently reduces serum and urine levels of thymidine and deoxyuridine, but not CSF levels and neurological function
by: Benjamin Röeben, et al.
Published: (2017-08-01)

Design, Synthesis, and In Vitro Antiproliferative Activity of Hydantoin and Purine Derivatives with the 4-Acetylphenylpiperazinylalkyl Moiety
by: Agnieszka Zagórska, et al.
Published: (2021-07-01)

Thymidine Phosphorylase Is Increased in COVID-19 Patients in an Acuity-Dependent Manner
by: Wei Li, et al.
Published: (2021-03-01)

Targeting thymidine phosphorylase inhibition in human colorectal cancer xenografts
by: Nathalia D. de Moura Sperotto, et al.
Published: (2021-07-01)

Quantification of Plasma and Urine Thymidine and 2’-Deoxyuridine by LC-MS/MS for the Pharmacodynamic Evaluation of Erythrocyte Encapsulated Thymidine Phosphorylase in Patients with Mitochondrial Neurogastrointestinal Encephalomyopathy
by: Karin Kipper, et al.
Published: (2020-03-01)

Safety and Efficacy of Erythrocyte Encapsulated Thymidine Phosphorylase in Mitochondrial Neurogastrointestinal Encephalomyopathy
by: Michelle Levene, et al.
Published: (2019-04-01)

Thymidine Phosphorylase Expression and Microvascular Density Correlation Analysis in Canine Mammary Tumor: Possible Prognostic Factor in Breast Cancer
by: Nicola Zizzo, et al.
Published: (2019-10-01)

Expression and Retention of Thymidine Phosphorylase in Cultured Reticulocytes as a Novel Treatment for MNGIE
by: Marjolein Meinders, et al.
Published: (2020-06-01)

Erythrocyte Encapsulated Thymidine Phosphorylase for the Treatment of Patients with Mitochondrial Neurogastrointestinal Encephalomyopathy: Study Protocol for a Multi-Centre, Multiple Dose, Open Label Trial
by: Bridget E. Bax, et al.
Published: (2019-07-01)

Influence of TYMP Polymorphism on Clinical Outcomes of Colorectal Cancer Patients Received Adjuvant Chemotherapy After R0 Resection
by: ZHANG Yu, et al.
Published: (2018-07-01)

Poor Outcome in a Mitochondrial Neurogastrointestinal Encephalomyopathy Patient with a Novel TYMP Mutation: The Need for Early Diagnosis
by: Mauro Scarpelli, et al.
Published: (2012-12-01)

Efficacy of adeno-associated virus gene therapy in a MNGIE murine model enhanced by chronic exposure to nucleosides
by: Ferran Vila-Julià, et al.
Published: (2020-12-01)

Modeling of 5-fluorouracil infulence on activity of its’ metabolic enzymes
by: M. Stashkevych
Published: (2015-11-01)

Trifluridine/tipiracil plus bevacizumab as a first‐line treatment for elderly patients with metastatic colorectal cancer (KSCC1602): A multicenter phase II trial
by: Eiji Oki, et al.
Published: (2021-01-01)

Mitochondrial Neurogastrointestinal Encephalomyopathy: Into the Fourth Decade, What We Have Learned So Far
by: Dario Pacitti, et al.
Published: (2018-12-01)

Preclinical Efficacy and Safety Evaluation of Hematopoietic Stem Cell Gene Therapy in a Mouse Model of MNGIE
by: Rana Yadak, et al.
Published: (2018-03-01)

Circulating miRNAs as Biomarkers for Mitochondrial Neuro-Gastrointestinal Encephalomyopathy
by: Mark Mencias, et al.
Published: (2021-04-01)

Assessment of the Angiogenic Potential of 2-Deoxy-D-Ribose Using a Novel in vitro 3D Dynamic Model in Comparison With Established in vitro Assays
by: Serkan Dikici, et al.
Published: (2020-01-01)

Compatibility and Fidelity of Mirror-Image Thymidine in Transcription Events by T7 RNA Polymerase
by: Qingju Liu, et al.
Published: (2020-09-01)

PDGF ENZYMATIC ACTIVITY IN PATIENTS WITH DELAYED FRACTURE CONSOLIDATION
by: D. V. Kuzmenko, et al.
Published: (2017-12-01)

Enhanced Anticancer Activity of 5’-DFUR-PCL-MPEG Polymeric Prodrug Micelles Encapsulating Chemotherapeutic Drugs
by: Alicia J. Sawdon, et al.
Published: (2018-12-01)

Chemotherapy-induced CDA expression renders resistant non-small cell lung cancer cells sensitive to 5′-deoxy-5-fluorocytidine (5′-DFCR)
by: Yanyun Gao, et al.
Published: (2021-04-01)

Studies on glycogen phosphorylase
by: Gilgan, Michael Wilson
Published: (2011)

Recent Updates on Mechanisms of Resistance to 5-Fluorouracil and Reversal Strategies in Colon Cancer Treatment
by: Shamin Azwar, et al.
Published: (2021-08-01)

Mitochondrial neurogastrointestinal encephalopathy: a clinicopathological mimic of Crohn’s disease
by: Ravi Patel, et al.
Published: (2019-01-01)

Strained Conformations of Nucleosides in Active Sites of Nucleoside Phosphorylases
by: Irina A. Il’icheva, et al.
Published: (2020-04-01)

Roles of NRF3 in the Hallmarks of Cancer: Proteasomal Inactivation of Tumor Suppressors
by: Akira Kobayashi
Published: (2020-09-01)

Mitochondrial neurogastrointestinal encephalomyopathy: A nonrenal indication for peritoneal dialysis
by: V S Chandra, et al.
Published: (2018-01-01)

Synthesis of new isoquinoline-base-oxadiazole derivatives as potent inhibitors of thymidine phosphorylase and molecular docking study
by: Ahmed, Q.U, et al.
Published: (2019)

Regulation of glycogen phosphorylase in hypoxic cancer cells
by: Mung, Kwan-long, et al.
Published: (2015)

Structural and functional dissection of the vaccinia virus thymidine kinase enzyme
by: Black, Margaret E.
Published: (2013)

Studies on chlorogenic acid in potatoes : effect of cold storage on changes in its content and in its inhibitory action of phosphorylase /
by: Hasegawa, Shin
Published: (1965)

Établissement de l’implication des α- et β-amylases et des α-glucanes phosphorylases au cours de la dégradation de l’amidon dans la feuille d’Arabidopsis thaliana
by: Devin, Aline
Published: (2010)

Enzymatic synthesis and phosphorolysis of 4(2)-thioxo- and 6(5)-azapyrimidine nucleosides by E. coli nucleoside phosphorylases
by: Vladimir A. Stepchenko, et al.
Published: (2016-12-01)