Développement de la radiosynthèse de la [¹¹C] sulfasalazine et du radiomarquage au fluor-18 d'aminoesters via un aziridinium pour l'imagerie TEP

Développement de la radiosynthèse de la [¹¹C] sulfasalazine et du radiomarquage au fluor-18 d'aminoesters via un aziridinium pour l'imagerie TEP

Les transporteurs d’acides aminés sont très souvent surexprimés au niveau des cellules tumorales et représentent une cible moléculaire privilégiée pour l’imagerie TEP (Tomographie par Emission de Positons) des cancers. Dans le but d’accéder à des radiotraceurs spécifiques de ces transporteurs, les t...

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Bibliographic Details
Main Author:	Morlot, Marine
Other Authors:	Normandie
Language:	fr
Published:	2017
Subjects:	TEP Carbone-11 Fluor-18 Aziridinium Transporteurs Xc- PET Radiochemistry Carbon-11 Fluorine-18 Fluoroaminoesters Xc- transporters Radioresistance
Online Access:	http://www.theses.fr/2017NORMC253

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