Caractérisation de nouveaux inhibiteurs de la kinase RIPK1 et de la nécroptose
La nécroptose est une mort cellulaire régulée impliquée dans les pathologies inflammatoires, ischémiques et dégénératives. RIPK1 serait une cible thérapeutique intéressante car son activité kinase serait à l’origine de leur initiation ou aggravation. Nous avons caractérisé les effets biologiques de...
Main Author: | Le Cann, Fabienne |
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Other Authors: | Rennes 1 |
Language: | fr en |
Published: |
2017
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Subjects: | |
Online Access: | http://www.theses.fr/2017REN1B012/document |
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