A novel role for prolyl-hydroxylase 3 gene silencing in epithelial-to-mesenchymal-like transition

The ability of cells to sense oxygen is a highly evolved process that facilitates adaptations to the local oxygen environment and is critical to energy homeostasis. In vertebrates, this process is largely controlled by three intracellular prolyl-4-hydroxylases (PHD 1-3). These related enzymes share...

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Bibliographic Details
Main Author: Place, Trenton Lane
Other Authors: Domann, Frederick
Format: Others
Language:English
Published: University of Iowa 2013
Subjects:
EMT
HIF
Online Access:https://ir.uiowa.edu/etd/1726
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=5778&context=etd