Graph theory analysis of single cell transcriptomes define islet signaling networks and cell identity

Several challenges face bioinformaticians on a regular basis. One of these is unsupervised clustering. In RNA sequencing (RNAseq), this may come in the form of blindly sequencing single cells without a priori knowledge of the cell types being sequenced. Here we create new methods to address this pro...

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Bibliographic Details
Main Author: Tyler, Scott Robert
Other Authors: Engelhardt, John F.
Format: Others
Language:English
Published: University of Iowa 2016
Subjects:
Online Access:https://ir.uiowa.edu/etd/2287
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=6746&context=etd