Graph theory analysis of single cell transcriptomes define islet signaling networks and cell identity
Several challenges face bioinformaticians on a regular basis. One of these is unsupervised clustering. In RNA sequencing (RNAseq), this may come in the form of blindly sequencing single cells without a priori knowledge of the cell types being sequenced. Here we create new methods to address this pro...
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Format: | Others |
Language: | English |
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University of Iowa
2016
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Online Access: | https://ir.uiowa.edu/etd/2287 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=6746&context=etd |