INVESTIGATING THE ROLE OF PRION PROTEIN POLYMORPHISMS ON PRION PATHOGENESIS
Transmissible spongiform encephalopathies (TSEs), also known as prion diseases, are lethal and infectious neurodegenerative diseases of humans and animals. The misfolding of the normal, or cellular isoform of the prion protein (PrPC) into the abnormal disease-associated isoform of PrP (PrPSc) could...
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UKnowledge
2012
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Online Access: | http://uknowledge.uky.edu/microbio_etds/4 http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1003&context=microbio_etds |