INVESTIGATING THE ROLE OF PRION PROTEIN POLYMORPHISMS ON PRION PATHOGENESIS

INVESTIGATING THE ROLE OF PRION PROTEIN POLYMORPHISMS ON PRION PATHOGENESIS

Transmissible spongiform encephalopathies (TSEs), also known as prion diseases, are lethal and infectious neurodegenerative diseases of humans and animals. The misfolding of the normal, or cellular isoform of the prion protein (PrPC) into the abnormal disease-associated isoform of PrP (PrPSc) could...

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Bibliographic Details
Main Author:	Saijo, Eri
Format:	Others
Published:	UKnowledge 2012
Subjects:	Prion Protein Species Barrier Prion Strain PrP Polymorphisms Zoonotic Potential Molecular and Cellular Neuroscience
Online Access:	http://uknowledge.uky.edu/microbio_etds/4 http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1003&context=microbio_etds

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