Regulation of Local Translation, Synaptic Plasticity, and Cognitive Function by CNOT7
Local translation of mRNAs in dendrites is vital for synaptic plasticity and learning and memory. Tight regulation of this translation is key to preventing neurological disorders resulting from aberrant local translation. Here we find that CNOT7, the major deadenylase in eukaryotic cells, takes on t...
| Main Author: | |
|---|---|
| Format: | Others |
| Published: |
eScholarship@UMMS
2017
|
| Subjects: | |
| Online Access: | https://escholarship.umassmed.edu/gsbs_diss/915 https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=1920&context=gsbs_diss |