Studies of structure-function relationship of components of multidrug efflux pumps and type I secretion systems
This work deals with channel-tunnel dependent multidrug efflux pumps and type I secretion systems, more concrete with the improved classification of the adaptor protein family, the characterization of the TolC-homologue protein HI1462 of Haemophilus influenzae, and the molecular characterization of...
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| Format: | Doctoral Thesis |
| Language: | English |
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2006
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| Online Access: | https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/1607 http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-18671 https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-18671 https://opus.bibliothek.uni-wuerzburg.de/files/1607/DissPolleichtner.pdf |
| Summary: | This work deals with channel-tunnel dependent multidrug efflux pumps and type I secretion systems, more concrete with the improved classification of the adaptor protein family, the characterization of the TolC-homologue protein HI1462 of Haemophilus influenzae, and the molecular characterization of the interaction between TolC and AcrA of Escherichia coli. === Diese Arbeit beschäftigt sich mit Channel-Tunnel-abhängigen Multidrug Efflux Pumpen und Typ I Sekretionssystemen, genauer gesagt mit der verbesserten Klassifikation der Familie der Adapter-Proteine, der Charakterisierung des TolC-homologen Proteins HI1462 aus Haemophilus influenzae, und der molekularen Charakterisierung der Interaktion zwischen TolC und AcrA aus Escherichia coli. |
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