Transcriptional functions of DNA Topoisomerases at a genome-wide scale and a single gene levels
The DNA topology is an important modifier of DNA functions. Torsional stress is generated when right handed DNA is either over- or underwound, producing structural deformations which drive or are driven by processes such as replication, transcription, recombination and repair. DNA topoisomerases are...
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| Format: | Doctoral Thesis |
| Language: | en |
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Alma Mater Studiorum - Università di Bologna
2010
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| Online Access: | http://amsdottorato.unibo.it/2970/ |