Involvement of microRNAs in Androgen Receptor-dependent Breast Cancers
Triple negative breast cancer (TNBC) is a very aggressive tumor subtype characterized by the lack of expression of estrogen receptor 1 (ESR1), due in the most of cases to an increased expression of DNA methyltransferases (DNMTs) and hypermethylation in CpG islands, resulting in gene silencing. Furth...
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Format: | Doctoral Thesis |
Language: | en |
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Alma Mater Studiorum - Università di Bologna
2015
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Online Access: | http://amsdottorato.unibo.it/6816/ |