Genomic imprinting: support for the concept from a study of Prader-Willi Syndrome patients
In this study, nineteen cases of suspected or clinically diagnosed Prader-Willi Syndrome (PWS) were tested for molecular deletions by in situ hybridization with two DNA probes, IR4-3R and GABRB3. Both probes are specific for sequences within the chromosome region 15q11-13, with IR4-3R located withi...
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Format: | Others |
Language: | English |
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University of North Texas
1994
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Online Access: | https://digital.library.unt.edu/ark:/67531/metadc332745/ |
Summary: | In this study, nineteen cases of suspected or clinically diagnosed Prader-Willi Syndrome (PWS) were tested for molecular deletions by in situ hybridization with two DNA probes, IR4-3R and GABRB3. Both probes are specific for sequences within the chromosome region 15q11-13, with IR4-3R located within the putative PWS region and GABRB3 in the distal area associated with Angelman Syndrome. |
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