The Transcriptional Repressor CC2D1A/Freud-1 Interacts with the Chromatin Remodeling Protein Brg1

The serotonin-1A (5-HT1A) receptor plays an important role in the regulation of the serotonin (5-HT) system as an autoreceptor on 5-HT neurons. The transcription factor CC2D1A/Freud-1 is a potent repressor of the 5-HT1A promoter in neuronal but not in non-neuronal cells. The clinical relevance of Fr...

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Bibliographic Details
Main Author: Mirédin, Kim
Other Authors: Albert, Paul
Language:en
Published: Université d'Ottawa / University of Ottawa 2012
Subjects:
Online Access:http://hdl.handle.net/10393/23148
http://dx.doi.org/10.20381/ruor-5912