Lifestyle Risk Factors Associated with Adult Primary Brain Tumours: Quality Assessment of Existing Systematic Reviews, Followed by Updated Analyses and De-Novo Syntheses
Background: A compilation of high quality systematic reviews (SRs) on lifestyle factors associated with adult glioma and meningioma was developed. Methods and Materials: Phase 1 consisted of a systematic overview of existing SRs. For Phase 2, high quality SRs were incorporated in an update. Moderat...
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ndltd-uottawa.ca-oai-ruor.uottawa.ca-10393-262432018-01-05T19:01:43Z Lifestyle Risk Factors Associated with Adult Primary Brain Tumours: Quality Assessment of Existing Systematic Reviews, Followed by Updated Analyses and De-Novo Syntheses Quach, Pauline Gomes, James Krewksi, Daniel Brain Tumours Glioma Meningioma Risk Factors Lifestyle Systematic Review Meta-Analysis Background: A compilation of high quality systematic reviews (SRs) on lifestyle factors associated with adult glioma and meningioma was developed. Methods and Materials: Phase 1 consisted of a systematic overview of existing SRs. For Phase 2, high quality SRs were incorporated in an update. Moderate or low quality SRs which had not been considered in a high quality review were eligible for a de-novo synthesis. Results: Phase 1 resulted in seven moderate to low quality reviews. From this, in Phase 2, smoking, mobile phone and hair dye use were subjected to de-novo reviews. For smoking, it was suggestive that past smokers had an increased risk. For mobile phone use, there was no overall association, however it was suggestive that ipsilateral and high cumulative call time were associated with slight increased risk. No association was observed for personal hair dye use. Conclusions: Despite these null associations, rigorous SR methods were used providing confidence in conveying these results. 2013-10-16T20:35:42Z 2013-10-16T20:35:42Z 2013 2013 Thesis http://hdl.handle.net/10393/26243 http://dx.doi.org/10.20381/ruor-3297 en Université d'Ottawa / University of Ottawa |
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en |
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topic |
Brain Tumours Glioma Meningioma Risk Factors Lifestyle Systematic Review Meta-Analysis |
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Brain Tumours Glioma Meningioma Risk Factors Lifestyle Systematic Review Meta-Analysis Quach, Pauline Lifestyle Risk Factors Associated with Adult Primary Brain Tumours: Quality Assessment of Existing Systematic Reviews, Followed by Updated Analyses and De-Novo Syntheses |
description |
Background: A compilation of high quality systematic reviews (SRs) on lifestyle factors associated with adult glioma and meningioma was developed.
Methods and Materials: Phase 1 consisted of a systematic overview of existing SRs. For Phase 2, high quality SRs were incorporated in an update. Moderate or low quality SRs which had not been considered in a high quality review were eligible for a de-novo synthesis.
Results: Phase 1 resulted in seven moderate to low quality reviews. From this, in Phase 2, smoking, mobile phone and hair dye use were subjected to de-novo reviews. For smoking, it was suggestive that past smokers had an increased risk. For mobile phone use, there was no overall association, however it was suggestive that ipsilateral and high cumulative call time were associated with slight increased risk. No association was observed for personal hair dye use.
Conclusions: Despite these null associations, rigorous SR methods were used providing confidence in conveying these results. |
author2 |
Gomes, James |
author_facet |
Gomes, James Quach, Pauline |
author |
Quach, Pauline |
author_sort |
Quach, Pauline |
title |
Lifestyle Risk Factors Associated with Adult Primary Brain Tumours: Quality Assessment of Existing Systematic Reviews, Followed by Updated Analyses and De-Novo Syntheses |
title_short |
Lifestyle Risk Factors Associated with Adult Primary Brain Tumours: Quality Assessment of Existing Systematic Reviews, Followed by Updated Analyses and De-Novo Syntheses |
title_full |
Lifestyle Risk Factors Associated with Adult Primary Brain Tumours: Quality Assessment of Existing Systematic Reviews, Followed by Updated Analyses and De-Novo Syntheses |
title_fullStr |
Lifestyle Risk Factors Associated with Adult Primary Brain Tumours: Quality Assessment of Existing Systematic Reviews, Followed by Updated Analyses and De-Novo Syntheses |
title_full_unstemmed |
Lifestyle Risk Factors Associated with Adult Primary Brain Tumours: Quality Assessment of Existing Systematic Reviews, Followed by Updated Analyses and De-Novo Syntheses |
title_sort |
lifestyle risk factors associated with adult primary brain tumours: quality assessment of existing systematic reviews, followed by updated analyses and de-novo syntheses |
publisher |
Université d'Ottawa / University of Ottawa |
publishDate |
2013 |
url |
http://hdl.handle.net/10393/26243 http://dx.doi.org/10.20381/ruor-3297 |
work_keys_str_mv |
AT quachpauline lifestyleriskfactorsassociatedwithadultprimarybraintumoursqualityassessmentofexistingsystematicreviewsfollowedbyupdatedanalysesanddenovosyntheses |
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1718597890513829888 |