The Mechanism of High MR Thioredoxin Reductase Investigated by Semisynthesis and Crystallography
The high Mr (~55 kDa) thioredoxin reductases (TR) characteristic of higher eukaryotes are members of the glutathione reductase (GR) family of pyridine nucleotide disulfide oxidoreductases. These homodimeric enzymes catalyze the reduction of a cognate disulfide substrate. During the enzymatic cycle,...
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| Format: | Others |
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ScholarWorks @ UVM
2007
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| Online Access: | http://scholarworks.uvm.edu/graddis/73 http://scholarworks.uvm.edu/cgi/viewcontent.cgi?article=1072&context=graddis |