DEVELOPMENT OF PPAR-γ RECEPTOR AGONISTS AS THERAPEUTIC AGENTS FOR DIABETES
The peroxisome proliferator-activated receptors (PPARs) are the transcriptional regulators of glucose, lipids and cholesterol metabolisms. It has been established that PPAR-γ is the receptor for thiazolidinediones (TZDs) class of type II anti-diabetic drugs. These compounds act as agonists of PPAR-γ...
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VCU Scholars Compass
2009
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| Online Access: | http://scholarscompass.vcu.edu/etd/1881 http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=2880&context=etd |