UNDERSTANDING THE FUNCTION OF DYRK1A THROUGH CHARACTERIZATION OF ITS INTERACTING PROTEINS
DYRK1A is a protein kinase encoded by a gene implicated in Down syndrome pathogenesis. Loss of DYRK1A could promote oncogenic transformation. However, the regulation and substrates of DYRK1A are not fully understood. MudPIT proteomic analysis revealed novel DYRK1A interacting proteins with poorly ch...
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| Format: | Others |
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VCU Scholars Compass
2015
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| Online Access: | http://scholarscompass.vcu.edu/etd/3719 http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=4749&context=etd |