Spectral methods for the detection and characterization of Topologically Associated Domains
The three-dimensional (3D) structure of the genome plays a crucial role in gene expression regulation. Chromatin conformation capture technologies (Hi-C) have revealed that the genome is organized in a hierarchy of topologically associated domains (TADs), sub-TADs, and chromatin loops which is relat...
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| Format: | Others |
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VCU Scholars Compass
2019
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| Online Access: | https://scholarscompass.vcu.edu/etd/6100 https://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=7201&context=etd |