Design, Synthesis, and Evaluation of Bicyclic Peptides as Ammonium Ionophores
A series of bicyclic peptides have been designed and synthesized to provide ammonium ion complexation sites via hydrogen bonding in a tetrahedral geometry. Molecular modeling dynamics and electrostatics studies indicate that target compounds 1d-6d may provide better selectivity for ammonium ions ov...
Main Author: | Nowak, Cheryl L |
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Other Authors: | W. Grant McGimpsey, Advisor |
Format: | Others |
Published: |
Digital WPI
2003
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Subjects: | |
Online Access: | https://digitalcommons.wpi.edu/etd-theses/434 https://digitalcommons.wpi.edu/cgi/viewcontent.cgi?article=1433&context=etd-theses |
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