A stochastic mathematical model of 4D tumour spheroids with real-time fluorescent cell cycle labelling

A stochastic mathematical model of 4D tumour spheroids with real-time fluorescent cell cycle labelling

In vitro tumour spheroids have been used to study avascular tumour growth and drug design for over 50 years. Tumour spheroids exhibit heterogeneity within the growing population that is thought to be related to spatial and temporal differences in nutrient availability. The recent development of real...

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Bibliographic Details
Main Authors: Browning, A.P (Author), Carr, E.J (Author), Gunasingh, G. (Author), Haass, N.K (Author), Klowss, J.J (Author), Murphy, R.J (Author), Plank, M.J (Author), Simpson, M.J (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
Subjects:
cancer
FUCCI
individual-based model
melanoma
population dynamics
Online Access:View Fulltext in Publisher

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