Remote Sensing System for Motor Nerve Impulse

• Main Authors: Barbilian, A. (Author), Blystad, L.-C (Author), Carbunaru, V. (Author), Costea, R. (Author), Dascalu, M. (Author), Dinulescu, S. (Author), Dobrescu, D. (Author), Dobrescu, L. (Author), Dragomir, D.C (Author), Franti, E. (Author), Gheorghe, M.-I (Author), Gherghiceanu, F. (Author), Hønsvall, B.K (Author), Imenes, K. (Author), Ion, M. (Author), Ionescu, O. (Author), Lascar, I. (Author), Marchetti, L. (Author), Mihailescu, C. (Author), Moldovan, C.A (Author), Neagu, T.P (Author), Niculae, C. (Author), Ohlckers, P.A (Author), Oproiu, A.M (Author), Predoi, G. (Author), Raita, S. (Author), Ramirez-Sarabia, J. (Author), Stoica, C. (Author)
• Format: Article
• Language: English
• Published: MDPI 2022
• Subjects: Biocompatibility; Controlled system; Fabrication process; Implantable devices; Implantable electrodes; Mammals; Micro technology; microfabrication; Micro-fabrication; microsystem; microtechnology; Nerve impulse; Neural prostheses; neuroprosthesis; Neuroprosthetic; Neurosurgery; Remote sensing; Remote sensing system; Research achievements; Well testing
• Online Access: View Fulltext in Publisher

 In this article, we present our research achievements regarding the development of a remote sensing system for motor pulse acquisition, as a first step towards a complete neuroprosthetic arm. We present the fabrication process of an implantable electrode for nerve impulse acquisition, together with an innovative wirelessly controlled system. In our study, these were combined into an implantable device for attachment to peripheral nerves. Mechanical and biocompatibility tests were performed, as well as in vivo testing on pigs using the developed system. This testing and the experimental results are presented in a comprehensive manner, demonstrating that the system is capable of accomplishing the requirements of its designed application. Most significantly, neural electrical signals were acquired and transmitted out of the body during animal experiments, which were conducted according to ethical regulations in the field. © 2022 by the authors. Licensee MDPI, Basel, Switzerland.