Deglutarylation of glutaryl-CoA dehydrogenase by deacylating enzyme SIRT5 promotes lysine oxidation in mice
A wide range of protein acyl modifications has been identified on enzymes across various metabolic processes; however, the impact of these modifications remains poorly understood. Protein glutarylation is a recently identified modification that can be nonenzymatically driven by glutaryl-CoA. In mamm...
Main Authors: | Adams, A.E (Author), Allie, C.M (Author), Anderson, K.A (Author), Backos, D.S (Author), Bhatt, D.P (Author), Francisco, S. (Author), Gomes, C.M (Author), Grimsrud, P.A (Author), Henriques, B.J (Author), Hirschey, M.D (Author), Ilkayeva, O.R (Author), Kulkarni, S.R (Author), Liu, J. (Author), Lucas, T.G (Author), Major, M.B (Author) |
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Format: | Article |
Language: | English |
Published: |
American Society for Biochemistry and Molecular Biology Inc.
2022
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Subjects: | |
Online Access: | View Fulltext in Publisher |
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