Evolution of gene expression signature in mammary gland stem cells from neonatal to old mice

Evolution of gene expression signature in mammary gland stem cells from neonatal to old mice

During the lifetime of females, mammary epithelial cells undergo cyclical expansion and proliferation depending on the cyclical activation of mammary gland stem/progenitor cells (MaSCs) in response to the change of hormone level. The structural shrink of mammary duct tree and the functional loss of...

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Bibliographic Details
Main Authors: Guo, Y. (Author), Huang, X. (Author), Li, S. (Author), Liu, P. (Author), Lü, J. (Author), Luo, A. (Author), Ma, W. (Author), Qian, L. (Author), Wang, G. (Author), Wang, H. (Author), Xu, Y. (Author), Yang, X. (Author), Yu, Z. (Author), Zhao, Q. (Author)
Format: Article
Language:English
Published: Springer Nature 2022
Subjects:
animal
Animals
cell transformation
Cell Transformation, Neoplastic
Epithelial Cells
epithelium cell
female
Female
genetics
Mammary Glands, Animal
metabolism
Mice
mouse
stem cell
Stem Cells
transcriptome
Transcriptome
udder
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