Circulating Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine Antigen Detected in the Plasma of mRNA-1273 Vaccine Recipients

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) proteins were measured in longitudinal plasma samples collected from 13 participants who received two doses of mRNA-1273 vaccine. Eleven of 13 participants showed detectable levels of SARS-CoV-2 protein as early as day 1 after first vaccin...

Full description

Bibliographic Details
Main Authors: Baden, L.R (Author), Cheng, C.-A (Author), Desjardins, M. (Author), Li, X. (Author), Novack, L. (Author), Ogata, A.F (Author), Powell, M. (Author), Senussi, Y. (Author), Sherman, A.C (Author), Von, S. (Author), Walt, D.R (Author)
Format: Article
Language:English
Published: Oxford University Press 2022
Subjects:
Online Access:View Fulltext in Publisher
LEADER 03215nam a2200877Ia 4500
001 10-1093-cid-ciab465
008 220420s2022 CNT 000 0 und d
020 |a 10584838 (ISSN) 
245 1 0 |a Circulating Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine Antigen Detected in the Plasma of mRNA-1273 Vaccine Recipients 
260 0 |b Oxford University Press  |c 2022 
300 |a 4 
856 |z View Fulltext in Publisher  |u https://doi.org/10.1093/cid/ciab465 
520 3 |a Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) proteins were measured in longitudinal plasma samples collected from 13 participants who received two doses of mRNA-1273 vaccine. Eleven of 13 participants showed detectable levels of SARS-CoV-2 protein as early as day 1 after first vaccine injection. Clearance of detectable SARS-CoV-2 protein correlated with production of immunoglobulin G (IgG) and immunoglobulin A (IgA). © 2021 The Author(s) 2021. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com. 
650 0 4 |a 2019-nCoV Vaccine mRNA-1273 
650 0 4 |a adult 
650 0 4 |a Antibodies, Viral 
650 0 4 |a antibody production 
650 0 4 |a antigen 
650 0 4 |a Article 
650 0 4 |a blood sampling 
650 0 4 |a clinical article 
650 0 4 |a clinical trial 
650 0 4 |a controlled study 
650 0 4 |a coronavirus disease 2019 
650 0 4 |a coronavirus nucleocapsid protein 
650 0 4 |a coronavirus spike glycoprotein 
650 0 4 |a COVID-19 
650 0 4 |a COVID-19 
650 0 4 |a COVID-19 Vaccines 
650 0 4 |a disease severity 
650 0 4 |a elasomeran 
650 0 4 |a genetics 
650 0 4 |a health care personnel 
650 0 4 |a human 
650 0 4 |a human tissue 
650 0 4 |a Humans 
650 0 4 |a immune responses 
650 0 4 |a immunoassay 
650 0 4 |a immunoglobulin A 
650 0 4 |a immunoglobulin A 
650 0 4 |a Immunoglobulin A 
650 0 4 |a immunoglobulin blood level 
650 0 4 |a immunoglobulin G 
650 0 4 |a immunoglobulin M 
650 0 4 |a limit of detection 
650 0 4 |a mrna 1273 
650 0 4 |a mRNA vaccine 
650 0 4 |a pilot study 
650 0 4 |a prevention and control 
650 0 4 |a protein blood level 
650 0 4 |a receptor binding 
650 0 4 |a RNA translation 
650 0 4 |a SARS-CoV-2 
650 0 4 |a SARS-CoV-2 antigens 
650 0 4 |a Severe acute respiratory syndrome coronavirus 2 
650 0 4 |a spike 
650 0 4 |a Spike Glycoprotein, Coronavirus 
650 0 4 |a spike protein, SARS-CoV-2 
650 0 4 |a virus antibody 
650 0 4 |a virus neutralization 
650 0 4 |a virus nucleocapsid 
650 0 4 |a virus spike 
650 0 4 |a virus spike protein 
650 0 4 |a young adult 
700 1 0 |a Baden, L.R.  |e author 
700 1 0 |a Cheng, C.-A.  |e author 
700 1 0 |a Desjardins, M.  |e author 
700 1 0 |a Li, X.  |e author 
700 1 0 |a Novack, L.  |e author 
700 1 0 |a Ogata, A.F.  |e author 
700 1 0 |a Powell, M.  |e author 
700 1 0 |a Senussi, Y.  |e author 
700 1 0 |a Sherman, A.C.  |e author 
700 1 0 |a Von, S.  |e author 
700 1 0 |a Walt, D.R.  |e author 
773 |t Clinical Infectious Diseases