Organoid Sensitivity Correlates with Therapeutic Response in Patients with Pancreatic Cancer

Purpose: Pancreatic ductal adenocarcinoma (PDAC) remains a significant health issue. For most patients, there are no options for targeted therapy, and existing treatments are limited by toxicity. The HOPE trial (Harnessing Organoids for PErsonalized Therapy) was a pilot feasibility trial aiming to p...

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Main Authors: Akshinthala, D. (Author), Berzin, T.M (Author), Besaw, R. (Author), Bockorny, B. (Author), Bullock, A.J (Author), Callery, M. (Author), Cohen, J. (Author), Conahan, C. (Author), Davis, R.B (Author), Gonzalez, R.S (Author), Grossman, J.E (Author), Hidalgo, M. (Author), Huang, L. (Author), Kent, T.S (Author), Lim, C. (Author), Muthuswamy, L. (Author), Muthuswamy, S.K (Author), Narasimhan, S. (Author), Perea, S. (Author), Peters, M.L.B (Author), Pleskow, D. (Author), Sawhney, M.S (Author), Schlechter, B. (Author), Smith, M. (Author), Tsai, L.L (Author)
Format: Article
Language:English
Published: American Association for Cancer Research Inc. 2022
Online Access:View Fulltext in Publisher