VCP suppresses proteopathic seeding in neurons
Background: Neuronal uptake and subsequent spread of proteopathic seeds, such as αS (alpha-synuclein), Tau, and TDP-43, contribute to neurodegeneration. The cellular machinery participating in this process is poorly understood. One proteinopathy called multisystem proteinopathy (MSP) is associated w...
Main Authors: | , , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BioMed Central Ltd
2022
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Subjects: | |
Online Access: | View Fulltext in Publisher |
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by Ayala, Y., Bieschke, J., Buscher, W.J, Clemen, C.S, Davis, A.A, Dhavale, D., Diamond, M.I, French, R., Kaleelurrrahuman, M.S, Kotzbauer, P., Maggiore, G., Patterson, J.N, Pittman, S., Sun, Y., Vaquer-Alicea, J., Weihl, C., Zhu, J.
Published 2022
View Fulltext in PublisherPublished 2022
Article