Expression of CD39 Identifies Activated Intratumoral CD8+ T Cells in Mismatch Repair Deficient Endometrial Cancer

Expression of CD39 Identifies Activated Intratumoral CD8+ T Cells in Mismatch Repair Deficient Endometrial Cancer

Identification of human cancer-reactive CD8+ T cells is crucial for the stratification of patients for immunotherapy and determination of immune-therapeutic effects. To date, these T cells have been identified mainly based on cell surface expression of programmed cell death protein 1 (PD-1) or co-ex...

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Bibliographic Details
Main Authors: Bremer, E. (Author), de Bruyn, M. (Author), Elsinga, P.H (Author), Kol, A. (Author), Lubbers, J.M (Author), Nijman, H.W (Author), Paijens, S.T (Author), Plat, A. (Author), Spierings, D.C.J (Author), van Rooij, N. (Author), Vlaming, M.R (Author), Ważyńska, M.A (Author), Workel, H.H (Author)
Format: Article
Language:English
Published: MDPI 2022
Subjects:
CD103
CD39
exhaustion
PD-1
TGF-β
Online Access:View Fulltext in Publisher

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