Phosphorylation of cPLA2α at Ser505 Is Necessary for Its Translocation to PtdInsP2-Enriched Membranes
Group IVA cytosolic phospholipase A2α (cPLA2α) is a key enzyme in physiology and pathophysiology because it constitutes a rate-limiting step in the pathway for the generation of pro- and anti-inflammatory eicosanoid lipid mediators. cPLA2α activity is tightly regulated by multiple factors, including...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
NLM (Medline)
2022
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Subjects: | |
Online Access: | View Fulltext in Publisher |
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