Isolating the white matter circuitry of the dorsal language stream: Connectome-Symptom Mapping in stroke induced aphasia

Isolating the white matter circuitry of the dorsal language stream: Connectome-Symptom Mapping in stroke induced aphasia

The application of ℓ1-regularized machine learning models to high-dimensional connectomes offers a promising methodology to assess clinical-anatomical correlations in humans. Here, we integrate the connectome-based lesion-symptom mapping framework with sparse partial least squares regression (sPLS-R...

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Bibliographic Details
Main Authors: Baboyan, V. (Author), Basilakos, A. (Author), Bonilha, L. (Author), Fridriksson, J. (Author), Hickok, G. (Author), Rorden, C. (Author), Yourganov, G. (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
adult
aged
Aged
aphasia
Aphasia
arcuate fasciculus
area spt
Article
brain cortex
Cerebral Cortex
cerebrovascular accident
cohort analysis
complication
conduction aphasia
connectome
connectomics
diagnostic imaging
dorsal premotor cortex
female
Female
frontal lobe
human
Humans
insula
left hemisphere
Magnetic Resonance Imaging
major clinical study
male
Male
middle aged
Middle Aged
nerve cell network
Nerve Net
nuclear magnetic resonance imaging
partial least squares
partial least squares regression
pathology
pathophysiology
predictive value
premotor cortex
speech repetition
Stroke
superior longitudinal fasciculus
supramarginal gyrus
temporal cortex
temporal lobe
white matter
White Matter
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